Research Progress on the Treatment of Knee Osteoarthritis with Traditional Chinese Medicine
Abstract
Knee osteoarthritis (KOA) is a chronic degenerative disease commonly found in middle-aged and elderly people, characterized mainly by degenerative changes in knee joint cartilage and secondary bone hyperplasia. The exact mechanism of knee osteoarthritis is not yet clear, and Western medicine primarily focuses on symptomatic treatment, which cannot effectively curb the progression of the disease. With the continuous research and innovation in traditional Chinese medicine (TCM), TCM has shown advantages such as minimal side effects, significant and stable therapeutic effects, and relatively low costs. Thus, TCM methods for treating knee osteoarthritis have been widely applied in clinical practice. This article reviews the relevant mechanisms and pathways of knee osteoarthritis by searching literature from databases such as China National Knowledge Infrastructure (CNKI), PubMed, and Wanfang from 2003 to 2024, and provides an overview of the treatment of knee osteoarthritis from the perspectives of TCM monotherapy and compound TCM formulations.
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